
[Met5]-Enkephalin, amide
CAS No. 60117-17-1
[Met5]-Enkephalin, amide ( 5-Methionine-enkephalin amide )
产品货号. M29954 CAS No. 60117-17-1
[Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors.Met-enkephalin circulates in several forms, some of which may be derived from proteins other than proenkephalin A, and plasma levels of both free native, and peptidase-derivable Met-enkephalin are modulated physiologically.
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
10MG | ¥346 | 有现货 |
![]() ![]() |
25MG | ¥706 | 有现货 |
![]() ![]() |
100MG | 获取报价 | 有现货 |
![]() ![]() |
200MG | 获取报价 | 有现货 |
![]() ![]() |
500MG | 获取报价 | 有现货 |
![]() ![]() |
生物学信息
-
产品名称[Met5]-Enkephalin, amide
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述[Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors.Met-enkephalin circulates in several forms, some of which may be derived from proteins other than proenkephalin A, and plasma levels of both free native, and peptidase-derivable Met-enkephalin are modulated physiologically.
-
产品描述[Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors.Met-enkephalin circulates in several forms, some of which may be derived from proteins other than proenkephalin A, and plasma levels of both free native, and peptidase-derivable Met-enkephalin are modulated physiologically. (In Vitro):[Met5]-Enkephalin at 0.1 nM, 10 nM, and 1 μM significantly reduces the total number of glial cells in culture. [Met5]-Enkephalin, amide acts via δ-opioid receptor to inhibit pelvic nerve-evoked contractions of cat distal colon. [Met5]-enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC50 value of 2.2 nM. [Met5]enkephalin at a concentration (3 nM) which produces a large inhibition of neurogenic contractions, has no effect on contractions to exogenous acetylcholine.
-
体外实验[Met5]-Enkephalin at 0.1 nM, 10 nM, and1 μM significantly reduces the total number of glial cells in culture. [Met5]-Enkephalin, amide acts via δ-opioid receptor to inhibit pelvic nerve-evoked contractions of cat distal colon. [Met5]-enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC50 value of 2.2 nM. [Met5]enkephalin at a concentration (3 nM) which produces a large inhibition of neurogenic contractions, has no effect on contractions to exogenous acetylcholine.
-
体内实验——
-
同义词5-Methionine-enkephalin amide
-
通路Others
-
靶点Other Targets
-
受体δ and ζ opioid receptor
-
研究领域——
-
适应症——
化学信息
-
CAS Number60117-17-1
-
分子量572.68
-
分子式C27H36N6O6S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称Sequence:Tyr-Gly-Gly-Phe-Met-NH2
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
Stiene-Martin A, et al. Glial growth is regulated by agonists selective for multiple opioid receptor types in vitro. J Neurosci Res. 1991 Aug;29(4):538-48.
产品手册




关联产品
-
Lawsone
Lawsone(2-羟基-1,4-萘醌),也称为鞣酸,是一种红橙色染料,存在于指甲花植物 (Lawsonia inermis) 的叶子以及水葫芦 (Eichhornia crassipes) 的花中。
-
Primaquine diphospha...
伯氨喹是唯一普遍可用的可预防间日疟和卵形疟复发的抗疟药,也是唯一有效的恶性疟疾杀配子细胞剂。
-
Potassium 7-hydroxy-...
7-羟基-1-萘磺酸钾天然存在于茜草科栀子花的果实、鸢尾科番红花的花以及玄参科玄参科的花和叶中。